Transcription Factor Stat3 Monocyte-Derived Macrophages via the IL-10 Induces IL-10 in Primary Human
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منابع مشابه
IL-10 induces IL-10 in primary human monocyte-derived macrophages via the transcription factor Stat3.
IL-10 is an important immunosuppressive cytokine that can down-regulate expression of other cytokines and has been shown to down-regulate itself. We show, in this study, that treatment of human monocyte-derived macrophages with IL-10 induces IL-10 mRNA in a dose- and time-dependent manner with an optimum induction at 100 ng/ml and at 6 h, whereas IL-10-induced IL-10 protein can be detected at 1...
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تاریخ انتشار 2007